ODCs

Cytoscape Web

Click node...

Isolated plagiocephaly

1 OMIM reference -
2 associated genes
11 signs/symptoms

PROTEIN INTERACTIONS: 1

Chronic myeloid leukemia

1 OMIM reference -
3 associated genes
No signs/symptoms info

Isolated plagiocephaly

Chronic myeloid leukemia

FGFR3	(UniProt - OMIM)		ABL1	(UniProt - OMIM)
TCF12	(UniProt - OMIM)		BCR	(UniProt - OMIM)
			RUNX1	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	TCF12	(0.63)	RUNX1

Citations in the biomedical literature:

Isolated plagiocephaly		Chronic myeloid leukemia
	Synonym(s): - Non-syndromic unicoronal synostosis - Synostotic plagiocephaly		Synonym(s): - Chronic granulocytic leukemia - Chronic myelogenous leukemia

	Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare eye disease - Rare genetic disease		Classification (Orphanet): - Rare hematologic disease - Rare oncologic disease

	Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -		Classification (ICD10): - Neoplasms -

	Epidemiological data: Class of prevalence: 1-5 / 10 000 Average age onset: neonatal/infancy Average age of death: normal Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: adulthood Average age of death: - Type of inheritance: sporadic

	External references: 1 OMIM reference - No MeSH references		External references: 1 OMIM reference - No MeSH references

Isolated plagiocephaly
	Very frequent - Facial structural asymmetry / facial hemiatrophy / facial hemihypertrophy - Frontal bossing / prominent forehead - Plagiocephaly Frequent - Abnormal eye movements / oculomotor disorder - Abnormal visual field / hemianopsia / hemianopia / scotoma / visual peripheral rim - Strabismus / squint Occasional - Autosomal dominant inheritance - Hearing loss / hypoacusia / deafness - Intellectual deficit / mental / psychomotor retardation / learning disability - Macrocephaly / macrocrania / megalocephaly / megacephaly - Mid-facial hypoplasia / short / small midface
Chronic myeloid leukemia
(no data available)